It plays during the climax, with millions of lives just minutes away from certain death and Batman attacks the truck in The Bat. Now while it is great action music, it's true genius is in the way it reflects the characters during that scene. Not just in the way it calls back to the train fight in Begins, bringing the Al Ghul family full circle in their fates but for Batman himself.
Throughout Begins, we often associate the lone singing in the soundtrack with Bruce's childhood innocence, mourning his parents before him. In Rises this returns during the track, as the small boy has become Batman and is at the point of no return. The mere thought this invokes is inspiring; To think that child, that simple young boy became such a larger than life character as the Caped Crusader, struggling to save his city once and for all. We often view these superheroes as big impossibilities and here we're reminded that the Goddamn Batman was a simple child as we all have been. Sure, we've seen him grow up throughout the films but as the music reflects it becomes pretty mind-blowing.
But that's only half of what makes it so good. As the choir boy sings, there is also the chant, almost trying to drown it out in its ferocity. The conflicting styles of music, one simple and beautiful, while the other thunderous and vast. It evokes Bruce's internal struggle with the Batman, the innocence is still in there inside the beast. It represents what Bruce could've become (a ruthless tyrant like Bane or a happy, peaceful man), and the confrontation of Bat and Demon. Making the climax far more personal and emotional than most other action films. The score delivers themes more subtly and brilliantly than simple dialogue could've done, and it all comes to a head in this track.