I think Leo might have a big year. Between Gatsby and Unchained he has a good chance of at least a nom. Also JGL I really hope gets a nom with Lincoln best supporting, assuming it is good.
Also Pitt has big things lined up, WWZ and Twelve Years a Slave, who knows if he will be in the races.
For best director I'm keeping my eye on Alfonso Cuarón he might fly under the radar in conversation leading up to the Oscars but given his amazing history (Children of Men people!) I think he has a legit chance.